The DNCB-induced AD group showed an increase in serum total IgE (203.0 ng/mL), IL-4 (25.8 pg/mL), and TSLP (328.0 pg/mL), but serum total IgE (142.9 ng/mL), IL-4 (18.5 pg/mL), and TSLP (234.2 pg/mL) were significantly lower in the DNCB/LCE group (Figure 1E–G). Here, IGHE is linked to Alzheimer disease.