FGFR1 and central nervous system cancer: Additionally there are two case reports of young adults (22 and 32 years of age) with recurrent spinal lower grade gliomas: In the first one, a FGFR1-TACC1 was present at initial diagnosis [72], while the second patient developed FGFR1-TACC1 fusion only at recurrence of the tumor 14 years after the initial treatment by gross total resection [73].