For VLPs, this tool has been applied in combination with TEM to observe the size and corroborate the morphology of SARS-CoV-2 VLPs [113], influenza H7N9 VLPs (120 nm) [114], and Macrobrachium rosenbergii nodavirus VLPs (27-30 nm) targeting epidermal growth factor receptor (EGFR)-positive colorectal cancer cells [115]. Here, EGFR is linked to colorectal cancer.