ISG15 and type 2 diabetes mellitus: However, the mRNA expression of CMPK2, CXCL10, IFI35, IFT1, ISG15, RSAD2, and USP18 was up-regulated in HAECs after low-dose radiation, while that of CMPK2, CXCL10, IFT1, ISG15, RSAD2, and USP18 was up-regulated in T2D-HAEC, which was not consistent with the RNA-seq results.