LRG1 and obesity due to melanocortin 4 receptor deficiency: Multinomial regression analysis revealed that adolescents with higher levels of plasma LRG1 were 2.5 times more likely to be obese after adjusting for multiple potential confounders suggesting that LRG1 might be an early obesity marker as the difference in plasma LRG1 levels between overweight and obese adolescents was not significant.