AKT1 and neoplasm: The anti-tumor response of this peptide was found to be dose-dependent, inhibiting the proliferation of TNBC cell lines MDA-MB-231 and HCC1937 and suppressing tumor growth, but not T47D cells, through phosphatidylinositol-3-kinase (PI3K)/V-akt murine thymoma viral oncogene homolog (AKT) signaling [30].