ABCB1 and osteosarcoma: ABCB1 mRNA level in the SK-N-BE(2) neuroblastoma, Saos-2 osteosarcoma, and Daoy medulloblastoma cells was lower than it was in the SH-SY5Y cells, whereas ABCB1 expression in the RD rhabdomyosarcoma cell line was comparable with that in the negative control cells (Figure 1A).