STAT3 and neoplasm: Nasuno et al. found that MSCs achieve tumor suppression through mechanisms such as induction of apoptosis and control of cell division [150] Chen et al. found that BMMSCs reduce the risk of tumor formation due to colitis and that MSCs reduce inflammation at the bulk level, decrease the expression of pro-inflammatory factors, downregulate STAT3 phosphorylation expression, reduce tumor number, and decrease tumor load [151].