IL10 and inflammatory bowel disease: Kotlarz et al. performed genetic testing for IL-10, IL-10R1, and IL-10R2 in 66 patients with IBD with an age of onset younger than five years and found a total of 16 patients with these genetic defects, 5 of whom underwent allogeneic HSCT and did not experience a relapse during the subsequent 2-year follow-up period [104].