Our results showed that CHD5 expression was negatively correlated with the stroma score in KIPAN, SARC, Glioma, ACC, PCPG, LGG, KIRP, KIRC, LUSC, HNSC, and BRCA (Figure A4A), and it was significantly positively correlated with the stroma score in COADREAD, STES, STAD, ESCA, UVM, PRAD and CHOL (Figure A4B). This evidence concerns the gene CHD5 and central nervous system cancer.