IL17A and cystic fibrosis: However, given the well-known activation of the IL-23/IL-17 pathway in autoimmune chronic diseases such as Crohn’s or psoriasis [47,48], further studies will be needed to determine whether a local administration of this ‘cytokine mix’ might be desirable in more chronic lung conditions, such as cystic fibrosis, where lung pathogens such as P.a are also prominent.