Cebpb (CCAAT Enhancer Binding Protein Beta) and H2-k1 (Histocompatibility 2, K1, K region) are two proteins that play critical roles in regulating the cytokine-induced changes as observed during sepsis, and were significantly higher in the lung compared to the liver and kidney [15,33]. The gene discussed is CEBPB; the disease is Sepsis.