RYR1 and myopathy: There are other genes related with SAMS phenotypes such as COQ2, HTR7, RYR1, GATM, CYP3A4, CYP2D6, ABCC2, RYR2, CLCN1, VDR, and ABCG2. It was found that also the LPIN1 gene mutation may lead to myopathy and rhabdomyolysis in children [31].