CACNB2 and Brugada syndrome: Using co-transfected cells two cellular mechanisms with phenotype of BrS in presence of CACNB2 variant have been reported: the accelerated inactivation of L-type-Ca-current (variant: p.T11I) presenting BrS and reduced peak calcium current (variant: p.S481L) presenting an overlap of short QT syndrome and Brugada syndrome [12,22].