FOXM1 and hepatocellular carcinoma: We performed a class comparison analysis with t-tests and permutation tests (p < 0.001) of the class labels (FOXM1-high and -low) using BRB-ArrayTools (version 4.3.2) and identified 2119 genes differentially expressed between the classes (1275 genes upregulated and 844 downregulated in FOXM1-high HCC compared with FOXM1-low HCC) (Figure 2A).