This test can detect cancer in the patients’ urine and estimate the probability of its presence by extracting and quantifying these five mRNAs: MDK (migration and angiogenesis of the cancerous cells), HOX13 (affects cell differentiation), CDC2 (completion of cell cycle), IGFBP5 (inhibits the apoptosis) and CXCR2 (crucial for inflammatory response). This evidence concerns the gene IGFBP5 and cancer.