ROBO1 and urinary bladder carcinoma: Firstly, Sin et al. applied RNA sequencing tool for discovering bladder-cancer specific, 3-component mRNA panel, ergo urinary concentration of ROBO1 (promoter of tumor angiogenesis, BCa specific), WNT5A (regulation of cell polarity and migration, BCa specific) and CDC42BPB (the reference gene) mutational load.