There were four types of outcome measures: continuous measures of blood glucose, insulin and HbA1c; glucose and insulin tertiles; Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) scores; and the binary categories of elevated glucose, elevated HbA1c, ideal HbA1c, impaired glucose tolerance (IGT), and diabetes/T2DM. The gene discussed is INS; the disease is type 2 diabetes mellitus.