Furthermore, correction for the influences of stage and localization on PFS by a multivariate Cox PH model revealed HLA-A*02 as a statistically significant independent prognostic factor of PFS in our HNSCC cohort (HR 0.54; 95% CI: 0.31–0.92; p = 0.023; Figure 4a and Table S4). The gene discussed is HLA-A; the disease is head and neck squamous cell carcinoma.