The role of DDX3X in this kind of cancer has not been assessed, but it has been shown that in gastric, prostate and colon cancer cell lines, the interaction of DDX3X with YY1 is mediated by the circular DNA circ-CTNNB1, promoting tumor proliferation through the deregulation of the β-catenin axis [117]. This evidence concerns the gene DDX3X and colonic neoplasm.