Overexpression of DDX3X is a poor prognosis marker in gallbaldder carcinoma and pancreatic ductal ccarcinoma [47,48] and in pancreatic ductal carcinoma, DDX3X promotes p62 accumulation that in turn facilitates epithelial–mesenchymal transition and metastasis [49]. Here, DDX3X is linked to pancreatic ductal adenocarcinoma.