To evaluate the putative involvement of DDX3X and DDX5 interactors in specific types of cancer, a functional annotation was performed with respect to the DisGeNET (https://www.disgenet.org/, accessed on 8 April 2022) and the GAD (https://maayanlab.cloud/Harmonizome/dataset/GAD+Gene-Disease+Associations, accessed on 8 April 2022) databases implemented in DAVID. The gene discussed is DDX3X; the disease is cancer.