RBM39 and acute myeloid leukemia: A domain-focused CRISPR/Cas9 screen uncovered a network of interacting RBPs in AML that are essential for RNA splicing and AML survival including RBM39, which can be targeted by sulfonamides (including indisulum (also known as E7070), E7820, and chloroquinoxaline sulfonamide) [12,13].