IGF2 and neoplasm: The tumour types observed vary according to the BWSp molecular subgroups: cases with H19/IGF2:IG DMR GOM are usually predisposed to Wilms tumour, patients with KCNQ1OT1:TSS DMR LOM or CDKN1C pathogenic variants are predisposed to hepatoblastoma, rhabdomyosarcoma, or neuroblastoma, and patients with UPD(11)pat are predisposed to any of the tumour types observed in the BWS spectrum [2,10,12,15,21,22].