Taking into consideration the biochemical recurrence status of the samples (where available), we were able to identify seven proteins (NMP1, UQCRH, HSPA9, MRPL3, VCAN, SERBP1, HSPE1) as common denominators of PCa aggressiveness and persistence, which could potentially be used for the development of risk assessment tools. The gene discussed is HSPE1; the disease is posterior cortical atrophy.