Importantly, GAL/GALR expression has been correlated with tumor subtypes (colon carcinoma, squamous cell carcinoma, neuroblastic tumors, pituitary adenoma) or with tumor stage [101] and the activation of GAL1R was generally antiproliferative, whereas the activation of GAL2R showed antiproliferative or proliferative effects [101]. This evidence concerns the gene GALR2 and neoplasm.