GAL inhibited the proliferation of glioma cells and tumor growth via GAL1R [205]; a reduced level of GAL was observed in the cerebrospinal fluid of patients with glioblastoma [203], and GAL3R expression has been related to high-grade glioma [30]: the line of research on glioma must be developed in the future. This evidence concerns the gene GALR3 and central nervous system cancer.