Because GALRs play a crucial role in certain tumors, it is important to determine whether GALRs are involved in the viability of cancer cells, as has previously been demonstrated in tumor cells for the neurokinin-1 receptor [10] Moreover, the possible tumor and/or antitumor actions mediated by GAL fragments and other members of the GAL family of peptides such as GALP, spexin, alarin and GMAP must also be studied, since most of the studies in this field have focused on the entire molecule of GAL. The gene discussed is SPX; the disease is cancer.