In contrast, a recent multiomics study demonstrated that alterations in RTK and downstream MAPK signaling pathways, mostly gene amplification of KRAS (19.4%), FGFR2 (11.2%), MET (7.1%), ERBB2 (5.1%), and EGFR (4.1%), occur more frequently in cancer cells within malignant ascites than those in primary DGC [12] (Figure 1). This evidence concerns the gene FGFR2 and cancer.