Liu et al. generated transgenic mice in which the AR-V567es was placed under the control of the probasin (Pb) promoter, revealing significant increases in oncogenic K-RAS, FLI1, STK33, NF-κB, and β-linked protein signaling, suggesting that this AR-V can drive both tumor growth and the acquisition of castration resistance [99]. This evidence concerns the gene AR and neoplasm.