SH3TC2 and colon adenocarcinoma: Through the Cibersoft algorithm, we observed that SH3TC2 correlated with NK_cells_activated immune infiltration in COAD (R = −0.12, p = 0.042) and correlated with the immune infiltration level of T_cells_CD4_naive (R = −0.28, p = 0.007) and T_cells_gamma_delta (R = −0.22, p = 0.033) in READ (Figure 2B).