The results showed that high SH3TC2 expression predicted worse DFS for colon cancer patients (hazard ratio, HR = 2.20, p = 0.0015) and rectal cancer patients (HR = 4.00, p = 0.0084), while the level of SH3TC2 expression in SKCM (HR = 0.86, p = 0.22) and TGCT (HR = 0.66, p = 0.25) had no significant effect on DFS (Figure 1D). Here, SH3TC2 is linked to colonic neoplasm.