Song et al. showed that binding of long noncoding RNA HNF4A-AS1 to the RGG domain of hnRNPU facilitates hnRNPU–CTCF interaction leading to CTCF transactivation and subsequent transcriptional alteration of HNF4A and other cancer-associated genes in neuroblastoma (NB) cells [34]. This evidence concerns the gene HNF4A and cancer.