Co-primary endpoints were PFS in the intention-to-treat (ITT) and in PD-L1-positive (defined as IC covering ≥ 1% of the tumour area as determined by VENTANA SP142 PD-L1 assay) populations, and OS tested hierarchically in the ITT population and, if significant, in the PD-L1 IC-positive population. Here, CD274 is linked to neoplasm.