CCNG2 and colorectal carcinoma: For instance, regarding the oncogenic function of miR-1246, Wang et al. [58] demonstrated that this miRNA promoted proliferation and invasiveness of colorectal cancer (CRC) cell lines and protected them from apoptosis through negative regulation of the CCNG2 gene, which encodes cycling G2, an atypical cyclin that induces cell cycle arrest and is frequently downregulated in tumors.