Specifically, miR-485-3p was found to be upregulated in hepatocellular carcinoma, and to support tumor cell proliferation and survival in vitro and tumor growth and metastasis in mice by targeting the MAT1A gene, which encodes the α1 catalytic subunit of methionine adenosyltransferase [65]. The gene discussed is MAT1A; the disease is hepatocellular carcinoma.