Enhanced expression of miR-1246 in melanoma specimens with respect to normal tissue was recently reported by Yu et al. [39], who in addition demonstrated that miR-1246 promoted melanoma cell proliferation, survival and invasiveness by targeting FOXA2, a gene with a tumor-suppressor function in several types of cancer, including melanoma [83,84,85,86]. Here, FOXA2 is linked to neoplasm.