CXCR4 and glioblastoma: Recent studies have shown that chemokines expression of CXCL2, CX3CL1, CCL5, and CCL2 and chemokine receptors CCR5, CX3CR1, CXCR2, CXCR4, CXCR6m and CXCR7 are significantly high in glioblastoma tumors [71].