IL6 and sarcopenia: Secondly, it is known that skeletal muscle loss has a strong effect on the immune system, promoting an increase in pro-inflammatory cytokines, such as tumor growth factor (TGF-ß) and interleuchin-6 (IL-6), which play an important role in tumor growth, recurrence, and, consequently, in survival [26], even though, in our study a correlation between the cumulative incidence of relapse and sarcopenia was not found.