An interesting result of our meta-analysis is that the negative prognostic value of TERT upregulation in oral cancer showed no geographical differences (p = 0.27), which indicates in our view that the upregulation of this protein does not depend on etiological factors of oral cancer that act differently in different areas of the world, but probably represents a condition inherent to the biopathology of oral cancer. This evidence concerns the gene TERT and lip and oral cavity carcinoma.