TP53 and myeloid leukemia: Trp53 mice carrying gain of function point mutations do develop a broader range of cancers that is closer to human cancers with TP53 mutations and TP53-deficient hamsters with one major exception in that they do not develop myeloid leukemias, which are common in TP53 mutants (especially homozygous mutant) hamsters and in human myeloid leukemia patients.