Previously, the same group demonstrated that exposure to basic fibroblast growth factor (bFGF) ameliorates T2D-associated changes in clonogenic ability by ScAT-ASCs; however, bFGF was not investigated in this study [44] Other limitations include (1) lack of information from the clinician about the patient’s treatment which might influence the stemness of IPFP-ASCs and (2) all cells were isolated from patients undergoing knee arthroplasty in response to severe OA symptoms. Here, FGF2 is linked to type 2 diabetes mellitus.