ETV5 and cystic fibrosis: In addition, in CF sweat, the decreased levels of CFTR interactors, e.g., ERM proteins (EZR, MSN) or filamins, plus the under-expression of all the protein constituents of the desmosome highlighted: (i) the defects in CFTR homeostasis and membrane stability as well as cell-cell adherence and membrane integrity of the eccrine gland cells, (ii) the potential of sweat analysis to remotely monitor some aspects of CF pathophysiology in other epithelia.