To characterize the role of UGT2B28 in PCa, we established a series of genetic models in LNCaP, LAPC-4, and VCaP cells, in which we knocked down (KD) UGT2B28 expression using lentiviral shRNA (Supplementary Figure S3A) and rescued the expression by means of lentiviral-based re-expression of UGT2B28 (UGT2B28 R) (Figure 2A–C). This evidence concerns the gene UGT2B28 and posterior cortical atrophy.