Surgical vagotomy was able to reduce dysbiosis in mice with CCl4-induced cirrhosis, but these animals showed increased levels of brain-derived neurotrophic factor, a key protein involved in the pathogenesis of cirrhosis and associated complications, and inflammatory cytokines such as IL-1β and MCP-1, as well as increased liver steatosis [136]. This evidence concerns the gene BDNF and Cirrhosis.