The orally administration of gintonin (25, 50, or 100 mg/kg) for 3 weeks decreased scopolamine and amyloid-β-induced memory impairment and cholinergic dysfunctions through reduction of acetylcholine concentration, choline acetyltransferase activity and induction of acetylcholine esterase (AChE) activity [66]. Here, ACHE is linked to memory impairment.