HIF1A and non-small cell lung carcinoma: Our results demonstrated that the mechanisms linking intermittent hypoxia and chemo-immuno-resistance (i.e. the activation of mtROS/ HIF-1α C/EBP-β LAP axis) were the same in NSCLC cells, either sensitive or resistant under normoxic conditions, and that the chemo-immuno-sensitizer strategies proposed were effective in both cases.