Of the blood markers identified here as being relevant for the long-term outcome after stroke, arguably the most important molecular key players are tumor necrosis factor alpha (TNF), interleukin 6 (IL6), fibrinogen (FGA), and plasminogen activator inhibitor-1 (SERPINE1) (Donkel et al. 2019; Lai et al. 2019; Reiche et al. 2019; Alfieri et al. 2020; Lehmann et al. 2021). This evidence concerns the gene TNF and Stroke.