CXCR4 and B-cell chronic lymphocytic leukemia: The transcriptome of CLL cells was dominated by three main clusters identified across patients and characterized by different expression of CXCR4, CD27 and MIR155HG, respectively, which may represent the recirculation of CLL cells between peripheral blood and lymph nodes40–42 (Fig. 3f,g and Extended Data Fig. 7a–d).