ITGAX and neoplasm: For example, LPS ip injection to the xenograft mice modulated the macrophage phenotype polarization in blood and spleen, and changed M1 or M2 macrophage infiltration into the xenograft tumour and spleen (Masuda et al. 2018), and increased CD11c-Gr-1 macrophage infiltration in the lung (Rega et al. 2013).