Because of a significant interaction of mean HbA1c with both mean eGFR and mean Hb (P 0.007 and <0.0001, respectively), we performed a stratified analysis to estimate the CKD staging- and anemia-specific hazard ratios (HRs) of all-cause or cardiovascular mortality for various mean HbA1c levels. This evidence concerns the gene GSTM1 and anemia (phenotype).