To investigate the underlying mechanisms of the activation of the FGF2/FGFR1/FAPα axis in promoting tumor cell EMT and MDSC recruitment, the FGFR1-knockdown LX-2 cells were transfected with vector (LX-2siNCVector, LX-2siFGFR1Vector) or FAPα-overexpressing plasmid (LX-2siFGFR1Vector, LX-2siFGFR1FAP) (Supplemental Figure 11A). The gene discussed is FGFR1; the disease is neoplasm.