In addition, the SIAH1 protein levels were clearly increased in tumours obtained from patients with progression-free survival (PFS) > 6 months (clinically described as cDDP sensitive), whereas its expression was reduced in tumours obtained from patients with PFS < 6 months (cDDP resistant; Figure 1B, 1C and Supplementary Figure 1B). The gene discussed is SIAH1; the disease is neoplasm.