PTH and Hypercalcemia: Primary hyperparathyroidism (PHPT), a common endocrine disturbance, is defined by hypercalcemia caused by excessive uncontrolled secretion of PTH from the parathyroid glands.13,14 Parathyroid hormone is a considerable organizer of bone remodeling, the process of renewal of the skeleton that occurs continuously throughout life.15 Hypersecretion of PTH results in a rise in bone turnover, mostly in resorption, leading to a raised risk of fracture.2,14