The hormone receptor pattern in breast cancer patients is consistent with estrogen (47.1%) and progesterone (13.2%) receptors in Kumasi.11 A lower proportion (18%) of patients tested positive for estrogen receptor and/ or progesterone receptor from a similar study in Accra8 The difference in receptor pattern could be due to differences in methodologies used in the various studies, especially considering the minimal variations between the three cities (Accra, Kumasi and Cape Coast) in terms of the influence of demography and socioeconomic status. The gene discussed is ESR1; the disease is breast carcinoma.