NEAT1 and Alzheimer disease: As depicted in Figure 5(Fig. 5), ROC curve analysis on the NEAT1 level for AD versus control, leads to an AUC (area under the curves) of 0.85 (95 % CI: 0.776-0.924, p <0.0001) with 72 % sensitivity and 84 % specificity, indicating its good power on discriminating the AD patients from healthy controls (Figure 5a(Fig. 5)).