IL6 and COVID-19: The other hypothesis explains the decreased serum TSH levels in patients infected by SARS-CoV-2 through a distorted hypothalamic– pituitary–thyroid axis.23 A critical function of serum TSH is the inverse proportional association with interleukin-6 (IL-6) levels, which identifies inflammatory response to SARS-CoV-2.23 If the IL-6 level is high in patients with COVID-19, there is a possibility of ESS, and low TSH and T3 levels are found.