1955). However, further research indicated that that liver enzyme levels are not sensitive for the diagnosis of mild liver injury (Ozer et al. 2008). Patients with non-alcoholic fatty liver disease (NAFLD) can have normal ALT values (Mofrad et al. 2003; Fracanzani et al. 2008). Moreover, ALT values do not correlate well with liver disease severity noted on liver biopsy in subjects with chronic liver disease (Kallei et al. 1964). In fact, ALT and AST showed good specificity (both 100%) but poor sensitivity (9% and 11%) for discriminating liver disease severity (Rao et al. 2012). This evidence concerns the gene GPT and liver disorder.