IGHE and seasonal allergic rhinitis: They included: personalized pollen-related symptom-forecast information services for european patients with AR [16]; serum cytokine profiling as an indicator for personalized treatment of allergy [17]; validation of a new molecular multiplex IgE assay for the diagnosis and phenotipization of pollen allergy in the Mediterranean area [18]; implementation of digital technologies, such as online platforms for both patients and physicians, to improve the management of respiratory allergic diseases [19].